

Brand:Waters
Model:Synapt XS
Fixed Asset Number:S210000998
Affiliated Core:Multi-omics Mass Spectrometry Core
Location:115,Building B, Gaoke Innovation Center
Equipment Manager:Zhao Gongzheng, Zheng Ting, Li E
Contact:19129910970,zhaogz@szbl.ac.cn
1. MS³ Capability (MS/MS/MS): Acquires MS³ spectra for enhanced fragment ion information and higher confidence in identification (non-in-source CID).
2. Integrated Ion Mobility Separation: The ion mobility cell is positioned post-collision cell, enabling mobility separation for both MS and MS/MS spectra. Requires no pre-optimization with standards.
3. Ion Mobility Resolving Power Demonstration: Using isomeric peptides Ser-Asp-Gly-Arg-Gly and Gly-Arg-Gly-Asp-Ser (both [M+2H]²⁺ *m/z* 246.1) with collision cross sections (Ω) of 222.7 Ų and 211.7 Ų respectively, baseline separation is achieved with a resolving power (Ω/ΔΩ) >40.
4. CCS (Collision Cross Section) as Identification Metric: Provides CCS values as a complementary parameter for confident identification and improved quantification accuracy.
5. Mass Range:
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Quadrupole: *m/z* 20–16,000
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TOF: *m/z* 20–64,000
6. Resolution: Maintains resolution ≥80,000 FWHM at the instrument's maximum sampling rate.
7. HDX (Hydrogen-Deuterium Exchange) System: Integrated configuration.